WATPAHDTGTGSIAG - Who Are These People and How Did They Get Their Genomes Stuck in a Graph?

Force-Directed Graph


Graphy McBrowserface

This is a toy example of a graph genome browser. We did the following:

  1. Generate a population of chromosomes (GRCh38 chr22) with randomly-generated structural variants inserted, using SVGen.
  2. Build a population graph of the generated chromosomes plus the reference genome, using TwoPaCo. Dump the graph to GFA format.
  3. Create a GFA to JSONGraph.
  4. Implement several different Javascript-based viewers for JSONGraph data, using: